Metastatic versus metachronous adenoid cystic carcinoma in the lacrimal gland fossa: a case report
DOI:
https://doi.org/10.12809/hkjo-v25n1-301Keywords:
Carcinoma, adenoid cystic, Lacrimal apparatus, Multiparametric magnetic resonance imagingAbstract
A 53-year-old woman presented with a left painless enlarging lacrimal fossa lesion with hypoglobus and choroidal folds. 18 months earlier, she had undergone surgery and chemoradiotherapy for right maxillary sinus adenoid cystic carcinoma. After initial 1.5T magnetic resonance imaging, a double primary of left lacrimal gland adenoid cystic carcinoma with tricompartmental (frontal bone, lacrimal and temporalis fossa) involvement was suspected. However, subsequent high-field multi-parametric 3T magnetic resonance imaging suggested a solitary metastasis with a subperiosteal location and an uninvolved lacrimal gland. The solitary metastasis was confirmed intraoperatively and pathologically.
References
Shields JA, Shields CL, Epstein JA, Scartozzi R, Eagle RC Jr. Review: primary epithelial malignancies of the lacrimal gland: the 2003 Ramon L. Font lecture. Ophthalmic Plast Reconstr Surg 2004;20:10-21. DOI: https://doi.org/10.1097/01.IOP.0000103003.87842.BB
Tse DT, Kossler AL, Feuer WJ, Benedetto PW. Long-term outcomes of neoadjuvant intra-arterial cytoreductive chemotherapy for lacrimal gland adenoid cystic carcinoma. Ophthalmology 2013;120:1313-23. DOI: https://doi.org/10.1016/j.ophtha.2013.01.027
Woo KI, Kim YD, Sa HS, Esmaeli B. Current treatment of lacrimal gland carcinoma. Curr Opin Ophthalmol 2016;27:449-56. DOI: https://doi.org/10.1097/ICU.0000000000000301
Purohit BS, Vargas MI, Ailianou A, et al. Orbital tumours and tumour-like lesions: exploring the armamentarium of multiparametric imaging. Insights Imaging 2016;7:43-68. DOI: https://doi.org/10.1007/s13244-015-0443-8
Russo C, Strianese D, Perrotta M, et al. Multi-parametric magnetic resonance imaging characterization of orbital lesions: a triple blind study. Semin Ophthalmol 2020;35:95-102. DOI: https://doi.org/10.1080/08820538.2020.1742358
Chang HY, Jiang H, Zhou F. A rare case of metachronous triple cancers involving the tympanic membrane. Pak J Med Sci 2013;29:218-9. DOI: https://doi.org/10.12669/pjms.291.2490
Blanco M, Garcia-Fontan E, Rios J, Rivo JE, Fernandez-Martin R, Canizares MA. Pulmonar collision tumor: metastatic adenoid cystic carcinoma and lung adenocarcinoma. Rev Port Pneumol 2012;18:42-5. DOI: https://doi.org/10.1016/j.rppneu.2011.06.005
Lin WY, Hsu WH. Tumor-to-tumor metastasis: maxillary sinus adenoid cystic carcinoma metastasizing to double primary lung adenocarcinoma. Ann Thorac Surg 2010;90:e59-61. DOI: https://doi.org/10.1016/j.athoracsur.2010.06.063
Satake N, Yoshida S, Jinnouchi O, Sekita T. Adenoid cystic carcinoma of maxillary sinus with metastatic hepatocellular carcinoma. Case report. APMIS 2005;113:450-5. DOI: https://doi.org/10.1111/j.1600-0463.2005.apm_137.x
Park DY, Lee JH, Suh YL, Woo KI, Kim YD. Metastatic adenoid cystic carcinoma of the eyelid. Ophthalmic Plast Reconstr Surg 2012;28:e111-2. DOI: https://doi.org/10.1097/IOP.0b013e31823f63f0
Jedrych J, Galan A. Multiple cutaneous metastases: a rare and late sequelae of lacrimal gland adenoid cystic carcinoma. J Cutan Pathol 2013;40:341-5. DOI: https://doi.org/10.1111/cup.12054
Petrelli RL, Labay GR, Schwarz GS. Adenoid cystic carcinoma with orbital and cranial metastases: case report. Ann Ophthalmol 1978;10:611-5.
Kaur A, Harrigan MR, MeKeever PE, Ross DA. Adenoid cystic carcinoma metastatic to the dura: report of two cases. J Neurooncol 1999;44:267-73. DOI: https://doi.org/10.1023/A:1006352307507
Bacalja J, Magazin M, Ulamec M, Rako D, Trnski D, Kruslin B. Adenoid cystic carcinoma of the lacrimal gland metastatic to the kidney: case report and review of the literature. Scott Med J 2014;59:e14-7. DOI: https://doi.org/10.1177/0036933014530836
Maamari RN, Custer PL, Harocopos GJ. Incidentally discovered adenoid cystic carcinoma of the lacrimal gland with isolated liver metastases. Ocul Oncol Pathol 2017;3:262-6. DOI: https://doi.org/10.1159/000461585
Zeidan BA, Abu Hilal M, Al-Gholmy M, El-Mahallawi H, Pearce NW, Primrose JN. Adenoid cystic carcinoma of the lacrimal gland metastasising to the liver: report of a case. World J Surg Oncol 2006;4:66. DOI: https://doi.org/10.1186/1477-7819-4-66
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