Bilateral central serous chorioretinopathy secondary to endogenous hypercortisolism in Cushing disease: a case report
DOI:
https://doi.org/10.12809/hkjo-v30n1-410Keywords:
Central serous chorioretinopathy, Cushing syndrome, Pituitary ACTH hypersecretionAbstract
We report on a case of bilateral exudative retinal detachment secondary to fibrinous central serous chorioretinopathy (CSC) caused by endogenous hypercortisolism in Cushing disease in a 37-year-old man. The treatment-resistant CSC, along with Cushingoid features, raised the suspicion of underlying systemic conditions. Further examination confirmed an adrenocorticotropic hormone–secreting pituitary adenoma (Cushing disease). The patient underwent transsphenoidal adenoma resection. Cortisol levels normalized within 1 week, and the retinal detachment resolved without recurrence. To prevent irreversible vision loss, clinicians should consider the possibility of systemic causes, particularly in bilateral CSC refractory to treatment. Multifocal leakage points on angiography are suggestive of underlying systemic etiology.
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